Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2822729 | Genomics, Proteomics & Bioinformatics | 2010 | 6 Pages |
Abstract
Composition vector trees (CVTrees) are inferred from whole-genome data by an alignment-free and parameter-free method. The agreement of these trees with the corresponding taxonomy provides an objective justification of the inferred phylogeny. In this work, we show the stability and self-consistency of CVTrees by performing bootstrap and jackknife re-sampling tests adapted to this alignment-free approach. Our ultimate goal is to advocate the viewpoint that time-consuming statistical re-sampling tests can be avoided at all in using this alignment-free approach. Agreement with taxonomy should be taken as a major criterion to estimate prokaryotic phylogenetic trees.
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Authors
Guanghong Zuo, Zhao Xu, Hongjie Yu, Bailin Hao,