Computerized cognitive testing for patients with multiple sclerosis

Cognitive dysfunction affects 40–65% of multiple sclerosis (MS) patients. To date, conventional paper and pencil neuropsychological testing has been the method of choice for detecting deficits. However, the expense and lack of access to these tests make it difficult for many patients to obtain an assessment. With the introduction of computerized cognitive testing, certain barriers to assessment can be reduced. This paper critically reviews the currently available computerized batteries, including the Automated Neuropsychology Assessment Matrix (ANAM), the Mindstreams Computerized Cognitive Battery (MCCB), the Amsterdam Neuropsychological Tasks (ANT), the Cognitive Stability Index (CSI), and the Cognitive Drug Research (CDR) battery. Recent developments in this field show promise, although further research is required before this approach can be more widely implemented.

► We critically review the literature on computerized cognitive assessment in MS. ► Computerized batteries could reduce barriers to cognitive assessment. ► Computerized batteries reviewed include ANAM, MCCB, ANT, CSI, and CDR.