Article ID Journal Published Year Pages File Type
2825223 Trends in Genetics 2008 4 Pages PDF
Abstract

Using Arabidopsis microRNA (miRNA)-mediated gene regulation system as a model, we investigated how complex systems evolve with special attention to selection to maintain the systems. We found that the copy number of miRNA genes within each system is a key factor to determine the complexity of the system, indicating a crucial role of gene duplication to increase the complexity. Furthermore, we show that the mode of selection to maintain the systems depend on their complexity levels.

Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Genetics
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