| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2825538 | Trends in Genetics | 2008 | 5 Pages |
Abstract
Metazoan microRNAs (miRNAs) are commonly encoded by primary mRNA-like characteristics (mlRNAs). To investigate whether mlRNAs are subject to miRNA control, we compared the expression of mlRNAs to that of tissue-specific miRNAs. We show that, like mRNAs, the expression levels of predicted mlRNA targets are significantly reduced in tissues where a targeting miRNA is expressed. On the basis of these results, we describe a potential network for posttranscriptional miRNA-miRNA control.
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Authors
Yi Zhao, Shunmin He, Changning Liu, Songwei Ru, Haitao Zhao, Zhen Yang, Pengcheng Yang, Xiongyin Yuan, Shiwei Sun, Dongbo Bu, Jiefu Huang, Geir Skogerbø, Runsheng Chen,