| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2825677 | Trends in Genetics | 2006 | 9 Pages |
Abstract
More than a thousand quantitative trait loci (QTLs) relevant to many aspects of complex human disease have been identified in a wide range of rat inbred lines over the past few decades. With the complete rat genome available, it is now time for the next stage in rat genetic research: the identification and causal confirmation of underlying polymorphisms and genes. Recent developments in single nucleotide polymorphism-based genetic markers and technologies to manipulate the rat genome will undoubtedly be important tools in this next episode.
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Authors
Bart M.G. Smits, Edwin Cuppen,