Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2827613 | Blood Cells, Molecules, and Diseases | 2009 | 7 Pages |
Abstract
A novel Pro126His mutation in αIIb compromised transport of the pro-αIIbβ3 complex from the endoplasmic reticulum to the Golgi, leading to intracellular retention. The impaired αIIbβ3 transport is responsible for the thrombasthenia in this patient.
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Authors
Wei-Zhang Shen, Qiu-Lan Ding, Pei-Pei Jin, Xue-Feng Wang, Yu-Zhen Jiang, Shu-Mei Li, Hong-Li Wang,