Article ID Journal Published Year Pages File Type
2827613 Blood Cells, Molecules, and Diseases 2009 7 Pages PDF
Abstract
A novel Pro126His mutation in αIIb compromised transport of the pro-αIIbβ3 complex from the endoplasmic reticulum to the Golgi, leading to intracellular retention. The impaired αIIbβ3 transport is responsible for the thrombasthenia in this patient.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Molecular Biology
Authors
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