Article ID Journal Published Year Pages File Type
2828609 Journal of Structural Biology 2012 9 Pages PDF
Abstract
In conclusion, the structural data define a binding pattern for the recognition of sulfated molecules that can modulate the role of ECP in innate immunity. The results reveal the structural basis for the high affinity of ECP for glycosaminoglycans and can assist in structure-based drug design of inhibitors of the protein cytotoxicity to host tissues during inflammation.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Molecular Biology
Authors
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