Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2829380 | Journal of Structural Biology | 2007 | 9 Pages |
Abstract
A simple, fast and efficient noise-reduction protocol for three-dimensional electron tomographic reconstructions of biological material is presented. The approach is based on iterative application of median filtering and shows promise for automatic noise reduction as a pre-processor for automated data analysis tools which aim at segmentation, feature extraction and pattern recognition. The application of this algorithm produces encouraging results for a wide variety of experimental and synthetic electron tomographic reconstructions.
Keywords
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Molecular Biology
Authors
Peter van der Heide, Xiao-Ping Xu, Brad J. Marsh, Dorit Hanein, Niels Volkmann,