Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2829597 | Journal of Structural Biology | 2006 | 9 Pages |
Abstract
A new algorithm for computing electron microscopy tomograms which combines iterative methods with dual-axis geometry is presented. Initial modelling using test data shows several improvements over both the weighted back-projection and simultaneous iterative reconstruction technique methods, with increased stability and tomogram fidelity under high-noise conditions. Preliminary experimental dual-axis reconstructions confirm the viability of the new algorithm.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Molecular Biology
Authors
Jenna Tong, Ilke Arslan, Paul Midgley,