Article ID Journal Published Year Pages File Type
2829597 Journal of Structural Biology 2006 9 Pages PDF
Abstract

A new algorithm for computing electron microscopy tomograms which combines iterative methods with dual-axis geometry is presented. Initial modelling using test data shows several improvements over both the weighted back-projection and simultaneous iterative reconstruction technique methods, with increased stability and tomogram fidelity under high-noise conditions. Preliminary experimental dual-axis reconstructions confirm the viability of the new algorithm.

Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Molecular Biology
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