Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2831538 | Molecular Immunology | 2009 | 12 Pages |
Abstract
Exaggerated complement activation is a key event in the pathogenesis of a range of autoimmune and inflammatory diseases. Complement Receptor 1 (CR1) has emerged as a molecule of immense interest in gaining insight to the susceptibility, pathophysiology, diagnosis, prognosis and therapy of such diseases. This review brings forth a composite view of the current understanding on the structure, functions, genetics, disease associations and therapeutic implications of CR1.
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Authors
Rohan Khera, Nibhriti Das,