Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2833182 | Molecular Immunology | 2007 | 9 Pages |
Abstract
We conclude that the change in the transmembrane domain of the TCR-β chain affects TH1 T cells and the susceptibility to EAE, but does not affect TH2 cells. Investigating the molecular interaction within the TCR complex will help us to identify signalling pathways that can be manipulated to stop the progression of MS.
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Authors
Troels R. Petersen, Roleen Lata, Evelyn Spittle, B. Thomas Bäckström,