Percutaneous transcatheter closure of infarct related ventricular septal defects assisted with portable miniaturized extracorporeal membrane oxygenation: A case series

Infarct associated ventricular septal defects (VSDs) are associated with considerable morbidity and mortality and are typically treated via an open surgical approach with the assistance of full mechanical bypass support in the setting of cardiogenic shock. We present two patients with infarct related VSDs and cardiogenic shock (CS) following acute ST segment elevation myocardial infarction (STEMI) and a review of the literature. Each patient successfully underwent percutaneous transcatheter closure of infarct related VSDs and initiation of extracorporeal membrane oxygenation (ECMO) via a portable miniaturized system that resulted in improvement in the patients’ hemodynamics.