Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2839564 | Clínica e Investigación en Arteriosclerosis | 2014 | 9 Pages |
Abstract
In this paper we analize the in vitro effects of different statins over different cell lines from cells implicated in atherosclerotic process: endothelial cells, fibroblasts, and vascular muscular cells. In relation with our results we can proof that the effects of different dosis of different statins provides singular effects over growth curves of different cellular lines, a despite of a class-dependent effects. So, pleiotropic effects and its reversibility with mevalonate are different according with the molecule and the dosis.
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Authors
Jesús Millan Núñez-Cortés, Ysmael Alvarez Rodriguez, Granada Alvarez Novés, Carlos Recarte Garcia-Andrade, Luis Alvarez-Sala Walther,