Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2839725 | Clínica e Investigación en Arteriosclerosis | 2012 | 9 Pages |
Abstract
These findings indicate that the PPARβ/δ agonist GW501516 prevents IL-6-induced STAT3 activation by inhibiting ERK1/2 phosphorylation. These effects of GW501516 may contribute to the prevention of cytokine-induced insulin resistance in hepatic cells.
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Authors
LucÃa Serrano-Marco, Liliane Michalik, Walter Wahli, Manuel Vázquez-Carrera,