Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2844531 | Physiology & Behavior | 2012 | 5 Pages |
Abstract
⺠Bipolar disorder is associated with a high and progressive illness burden related to medical comorbidity, cognitive impairment and premature disability. ⺠In this report, we argue that allostasis is a meaningful concept in this context, possibly explaining much of the burden associated with bipolar disorder. ⺠It is explored how traditional mediators of allostasis relate to the systemic dysfunction and pathology found in bipolar disorder.
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Authors
Iria Grande, Pedro V. Magalhães, Mauricio Kunz, Eduard Vieta, Flavio Kapczinski,