Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2847597 | Respiratory Physiology & Neurobiology | 2010 | 10 Pages |
Abstract
This article examines the manner in which some new methodologies and novel concepts have contributed to our understanding of how pulmonary surfactant reduces alveolar surface tension. Investigations utilizing small angle X-ray diffraction, inverted interface fluorescence microscopy, time of flight-secondary ion mass spectroscopy, atomic force microscopy, two-photon fluorescence microscopy and electrospray mass spectroscopy are highlighted and a new model of ventilation-induced acute lung injury described. This contribution attempts to emphasize how these new approaches have resulted in a fuller appreciation of events presumably occurring at the alveolar interface.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Physiology
Authors
Fred Possmayer, Stephen B. Hall, Thomas Haller, Nils O. Petersen, Yi Y. Zuo, Jorge Bernardino de la Serna, Anthony D. Postle, Ruud A.W. Veldhuizen, Sandra Orgeig,