Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2848251 | Respiratory Physiology & Neurobiology | 2007 | 10 Pages |
The purpose of this study was to determine the effects of inspiratory muscle training (IMT) on exercise in hypoxia (H) and normoxia (N). A 4-week IMT program was implemented with 12 healthy subjects using an inspiratory muscle trainer set at either 15% (C; n = 5) or 50% (IMT; n = 7) maximal inspiratory mouth pressure (PImax). Two treadmill tests (85% V˙O2max) to exhaustion and measures of diaphragm thickness (Tdi) and function were completed before and after training in H and N. Significant increases of 8–12% and 24.5 ± 3.1% in Tdi and PImax, respectively, were seen in the IMT group. Time to exhaustion remained unchanged in all conditions. Inspiratory muscle fatigue (↓PImax) following exercise was reduced ∼10% (P < 0.05) in IMT after both N and H. During H, IMT reduced (P < 0.05) V˙O2 by 8–12%, cardiac output by 14 ± 2%, ventilation by 25 ± 3%; and increased arterial oxygen saturation by 4 ± 1% and lung diffusing capacity by 22 ± 3%. Ratings of perceived exertion and dyspnea were also significantly reduced. These data suggest that IMT significantly improves structural and functional physiologic measures in hypoxic exercise.