| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2864206 | The American Journal of the Medical Sciences | 2011 | 5 Pages |
Abstract
Acute renin inhibition with aliskiren normalizes MAP and RPF in Cyp1a1-Ren2 rats with malignant hypertension. The normalization of MAP and RPF after acute renin inhibition indicates that renin generated by expression of the Ren2 gene is responsible for the maintenance of malignant hypertension and the associated reduction in renal hemodynamic function in Cyp1a1-Ren2 rats.
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Authors
Catherine G. BS, Kenneth D. PhD, John J. PhD,