Human Immunodeficiency Virus Infection and Risk of Venous Thromboembolism

The incidence of VTE in patients with HIV infection was higher than in non-HIV patients. The incidence of VTE in patients with HIV in the postprotease inhibitor era (after 1996) was higher than in HIV patients before 1996, but the incidence was also higher in non-HIV patients after 1996. The higher incidence since 1996 is small, probably not clinically significant, and not necessarily because of protease inhibitors.