| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2869339 | Annales de Cardiologie et d'Angéiologie | 2007 | 5 Pages |
Abstract
Nt-proBNP have emerged as useful biomarker for the diagnosis and prognostic of heart failure but also recently in acute coronary syndrome. Myocardial ischemia is probably an important stimulus for Nt-proBNP release. Transient myocardial ischemia is inducing by balloon inflation during percutaneous coronary intervention (PCI). The authors propose to determine the Nt-proBNP secretion after uncomplicated coronary intervention in patients with preserved cardiac function. Ninety patients were enrolled in this study. Plasma Nt-proBNP was increased significantly from 135.5 to 157.8Â pg/ml and 202.5Â pg/ml at 8 and 24Â hours following PCI, respectively. History of myocardial infarction and complex lesions were the most powerful predictors of higher Nt-proBNP peak concentration. Prognostic value must be evaluated in larger studies.
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Authors
P. Schiano, F. Revel, Y. Hemery, J.-M. Ramirez, R. Haus, J.-P. Ollivier, J. Monségu,