Sirtuin1 Regulates the Stem Cell Therapeutic Effects on Regenerative Capability for Treating Severe Heart Failure in a Juvenile Animal Model

Article ID	Journal	Published Year	Pages	File Type
2870850	The Annals of Thoracic Surgery	2016	10 Pages	PDF

Abstract

Sirtuin1 expression in transplanted cells enhances the skeletal stem cell sheet therapeutic effects for treating severe heart failure in a juvenile animal model.

Keywords

NF-κB HGF LVEF HIF sirtuin SIRT SDF-1 MRI Magnetic resonance imaging Hepatocyte growth factor Hypoxia-induced factor Vascular endothelial growth factor Vascular Endothelial Growth Factor (VEGF)nuclear factor-κB Knockdown heart failure left ventricular ejection fraction

Related Topics

Health Sciences Medicine and Dentistry Cardiology and Cardiovascular Medicine

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Sirtuin1 Regulates the Stem Cell Therapeutic Effects on Regenerative Capability for Treating Severe Heart Failure in a Juvenile Animal Model

Authors

Hideto MD, Shigeru MD, PhD, Satsuki MD, PhD, Emiko PhD, Akima BD, Atsuhiro PhD, Takayoshi MD, PhD, Koichi MD, PhD, Toru MD, PhD, Yoshiki MD, PhD,