| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2870936 | The Annals of Thoracic Surgery | 2016 | 9 Pages |
Abstract
These results demonstrate that A2BR antagonism attenuates lung IRI and augments reconditioning of DCD lungs by EVLP. The protective effects of ATL802 may involve targeting A2BRs on alveolar epithelial cells to prevent IL-8 production. A2BR may be a novel therapeutic target for mitigating IRI to increase the success of lung transplantation.
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Authors
Mary E. MD, MA, Ashish K. MBBS, PhD, Yunge MD, PhD, Eric J. MD, Irving L. MD, Victor E. PhD,