Article ID Journal Published Year Pages File Type
2871464 The Annals of Thoracic Surgery 2016 6 Pages PDF
Abstract
Comparing patients receiving a loading dose of statins with those receiving a regular dose after CABG, the medium- and long-term efficacy of a loading dose showed significant reduction in LDL-C, lower occurrence of adverse cardiac events, and reduction in graft restenosis. Although the incidence of drug-related side effects was slightly higher in the loading-dose group, in the majority of patients they were not serious. Overall, a loading dose of statins is superior to regular dosing of statins after CABG.
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