Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2871905 | The Annals of Thoracic Surgery | 2015 | 9 Pages |
Abstract
Triptolide decreases lung cancer cell migration and invasion in vitro and inhibits metastatic tumor formation in mice. Triptolide suppresses focal adhesion kinase, which causes deregulation of the migration machinery. These results suggest that triptolide inhibits lung cancer metastasis and should be investigated as a new lung cancer therapy.
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Authors
Theresa A. PhD, Jae Y. MD, Dan J. MD,