Article ID Journal Published Year Pages File Type
2871905 The Annals of Thoracic Surgery 2015 9 Pages PDF
Abstract
Triptolide decreases lung cancer cell migration and invasion in vitro and inhibits metastatic tumor formation in mice. Triptolide suppresses focal adhesion kinase, which causes deregulation of the migration machinery. These results suggest that triptolide inhibits lung cancer metastasis and should be investigated as a new lung cancer therapy.
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