| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2874164 | The Annals of Thoracic Surgery | 2013 | 7 Pages |
Abstract
Minocycline limits microglial activation, paralleling functional preservation after aortic cross-clamping. These data suggest functional microglia contribute to reperfusion injury after spinal cord ischemia. The effects of minocycline demonstrate a potential pharmacological therapy as well as demonstrating a potential cellular target in preventing paraplegia after aortic intervention.
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Authors
Phillip D. MD, Marshall T. MD, Ferenc MD, PhD, Xianzhong MD, PhD, Joseph C. MD, Michael J. MD, David A. MD, T. Brett MD,