Association Between Obesity and Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Operations: A Systematic Review and Meta-Analysis

Article ID	Journal	Published Year	Pages	File Type
2874620	The Annals of Thoracic Surgery	2013	13 Pages	PDF

Abstract

In a systematic review and random-effects meta-analysis, we evaluated whether obesity is associated with postoperative atrial fibrillation (POAF) in patients undergoing cardiac operations. We selected 18 observational studies until December 2011 that excluded patients with preoperative AF (nÂ = 36,147). Obese patients had a modest higher risk of POAF compared with nonobese (odds ratio, 1.12; 95% confidence interval, 1.04 to 1.21; pÂ =Â 0.002). The association between obesity and POAF did not vary substantially by type of cardiac operation, study design, or year of publication. POAF was significantly associated with a higher risk of stroke, respiratory failure, and operative death.

Keywords

PRISMA RBC ACE CK-MB M-H HDL LVEF ECC FFP IABP PVD Cardiopulmonary bypass time ChF SPB Red blood cells ARBs BSA Myocardial infarction Angiotensin-converting enzyme Preferred Reporting Items for Systematic Reviews and Meta-Analyses Polyunsaturated fatty acid PUFA Finite element standard deviation intensive care unit ICU Cerebrovascular disease coronary artery disease Peripheral vascular disease COPD Chronic obstructive pulmonary disease coronary artery bypass grafting CABG standard error Not available Diabetes mellitus CVD body surface area body mass index BMI CAD confidence interval Atrial fibrillation postoperative atrial fibrillation high density lipoprotein low density lipoprotein LDL Mantel-Haenszel Meta-analysis Of Observational Studies in Epidemiology angiotensin II receptor blockers congestive heart failure Respiratory failure odds ratio Prospective cohort Retrospective cohort POAF fresh frozen plasma intraaortic balloon pump left ventricular ejection fraction ejection fraction extracorporeal circulation Moose