| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2874960 | The Annals of Thoracic Surgery | 2011 | 7 Pages |
Abstract
Ex-vivo lung perfusion demonstrates the ability to improve oxygenation and physiologic lung function in donor lungs unacceptable for transplantation without injury to the lung. We establish here a cytokine expression profile in human lungs undergoing normothermic EVLP. These data can be used in the future to explore novel targeted therapies for ischemia-reperfusion injury.
Keywords
PEEPTNFEVLPFiO2PaO2GM-CSFpCO2MCPinterleukinLeft atriumPulmonary arteryPVRgranulocyte colony-stimulating factorG-CSFtumor necrosis factorpartial pressure of arterial oxygenPartial pressure of carbon dioxidePositive end-expiratory pressuregranulocyte macrophage colony-stimulating factorPulmonary vascular resistancemonocyte chemotactic proteinFraction of inspired oxygen
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Authors
Miral R. MD, Phillip D. MD, David A. MD, George A. BS, CCP, LP, Joon H. MD, Ferenc MD, PhD, Frederick L. MD, Joseph C. MD, T. Brett MD, Michael J. MD,