Î±B-Crystallin Improves Murine Cardiac Function and Attenuates Apoptosis in Human Endothelial Cells Exposed to Ischemia-Reperfusion

Article ID	Journal	Published Year	Pages	File Type
2875609	The Annals of Thoracic Surgery	2011	7 Pages	PDF

Abstract

Exogenous CryAB administration significantly improves cardiac function after ischemia-reperfusion injury, in vivo. The protective anti-apoptotic affects of CryAB may target the endothelial cell.

Keywords

PBS HMEC TBS sHSP Hsp LVEF CRYAB I/R αB-crystallin ischemia-reperfusion Tris-buffered saline human microvascular endothelial cell LAD Phosphate-buffered saline Heat shock protein small heat shock protein left anterior descending artery left ventricular ejection fraction

Related Topics

Health Sciences Medicine and Dentistry Cardiology and Cardiovascular Medicine

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Î±B-Crystallin Improves Murine Cardiac Function and Attenuates Apoptosis in Human Endothelial Cells Exposed to Ischemia-Reperfusion

Authors

Jeffrey B. MD, Naoyuki MD, Stephanie H. BS, Jaehoon MD, Satoshi MD, Jonathan PhD, Philip C. MD, Lawrence MD, Robert C. MD, Michael P. MD, PhD,