Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2875702 | The Annals of Thoracic Surgery | 2014 | 9 Pages |
Abstract
Decellularized lung matrix supports the culture and lineage commitment of human iPSC-derived lung progenitor cells. Whole-organ scaffolds and biomimetic culture enable coseeding of iPSC-derived endothelial and epithelial progenitors and enhance early lung fate. Orthotopic transplantation may enable further in vivo graft maturation.
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Authors
Sarah E. PhD, Xi PhD, Tatsuya MD, PhD, Jacques P. PhD, Hongmei PhD, Jayaraj MD, Douglas J. MD, Joseph P. MD, Harald C. MD,