| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2876611 | The Annals of Thoracic Surgery | 2014 | 8 Pages |
Abstract
After cardiac surgery, infants who are homozygous for the high-risk alleles for both the VEGFA and SOD2 SNPs have an approximately 16-fold increased risk of death or heart transplant, suggesting that genetic variants are important modifiers of survival after surgery for congenital heart disease.
Keywords
EDN1TGACPBHLHSVEGFATOFCHDSOD2Myocardial infarctionEuropean ancestryTransposition of the great arteriesendothelin-1cardiopulmonary bypassTetralogy of FallotHypoplastic left heart syndromeSuperoxide dismutase 2Vascular endothelial growth factor ACongenital heart defectSingle nucleotide polymorphismSNP
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Authors
Daniel Seung BS, Jerry H. MD, Amber A. MS, David R. PhD, Nancy MSN, Donna M. MS, Elaine H. MD, Susan C. MD, Thomas L. MD, Ian B. BS, Deborah A. PhD, Mark W. MD, Hakon MD, PhD, J. William MD, Gail P. MD, PhD,