Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2877371 | The Annals of Thoracic Surgery | 2012 | 7 Pages |
Abstract
Lung ischemia reperfusion produces apoptosis and activation of the innate immune system including HMGB1 and TLR4 within 2 hours of reperfusion. Treatment with 20-5,14-HEDGE decreases activation of this response system, and salvages lung tissue.
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Authors
Irshad PhD, Stephanie BS, Ying MS, Anne PhD, John R. PhD, Meetha PhD, Elizabeth R. MD, MBA,