Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2877658 | The Annals of Thoracic Surgery | 2011 | 7 Pages |
Abstract
Intramyocardial injection of mesenchymal stem cells pretreated with TGF-α further protects cardiac function and reduces infarct size compared with injection of untreated cells. Pretreating donor cells with TGF-α may be useful for enhancing cell-based therapies for myocardial ischemia.
Keywords
MSCLVESDLVDPLVEFLVEDdTgf-αleft ventricleLeft ventricular developed pressuretransforming growth factor-αstandard error of the meanMesenchymal stem cellVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)left ventricular end-diastolic diameterleft ventricular end-systolic diameterLADSEMleft anterior descendingleft ventricular ejection fractionfractional shortening
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Authors
Jeremy L. MD, Aaron M. MD, Yue PhD, Brent R. MD, Jeffrey A. MD, Mariuxi C. MD, Daniel R. MD,