| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2878487 | The Annals of Thoracic Surgery | 2010 | 8 Pages |
Abstract
Using a large animal model and in vivo microdialysis measurements of plasmin activity, the unique findings from this study were twofold. First, EACA induced temporally distinct plasmin activity profiles within the plasma and interstitial compartments. Second, EACA caused region-specific changes in plasmin activity profiles. These temporal and regional heterogeneic effects of EACA may have important therapeutic considerations when managing fibrinolysis in the perioperative period.
Related Topics
Health Sciences
Medicine and Dentistry
Cardiology and Cardiovascular Medicine
Authors
Daryl L. MD, Scott T. MD, James H. MD, Jennifer A. MD, William F. BS, Rupak PhD, Christine N. BS, Robert E. MS, Francis G. MD, PhD,