| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2879315 | The Annals of Thoracic Surgery | 2008 | 5 Pages |
Abstract
Manipulation of human coronary arteries during off-pump operations leads to endothelial denudation and plaque rupture. From this investigation we conclude that insertion of intracoronary shunts during beating heart operations leads to severe endothelial denudation in human coronary arteries. We therefore recommend using shunts selectively in cases where critical ischemia or technical difficulties due to anatomic conditions are expected during anastomosis. The clinical significance of these structural damages has to be further investigated with clinical trials.
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Authors
Herbert MD, Ludwig MD, Elfriede MD, Herwig MD, Kristian PhD,