Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2880428 | The Annals of Thoracic Surgery | 2008 | 8 Pages |
Abstract
This study demonstrates that TLR4 signaling contributes to cardiac dysfunction after global ischemia/reperfusion. TLR4 signaling mediates the production of TNF-α and IL-1β peptides, and these two cytokines link TLR4 signaling to postischemic cardiac dysfunction.
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Authors
John MD, Zhiping MD, Lihua BS, Ning MD, PhD, Charles A. MD, Anirban PhD, David A. MD, Xianzhong MD, PhD,