| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2882479 | The Annals of Thoracic Surgery | 2008 | 9 Pages |
Abstract
Endocardial cushion formation is dependent on cell-specific expression of Bmpr1a. Our results suggest that Bmpr1a-mediated signaling is a crucial pathway involved in pathogenesis of atrioventricular septal and valve malformations, which are among the most common congenital heart defects in humans.
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Authors
Kan MD, PhD, Xiaodong MD, PhD, Xiaoxue MD, John J. MD, Stuart W. MB, FRCS, Patricia A. MD, PhD,