| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2883051 | The Annals of Thoracic Surgery | 2017 | 7 Pages |
Abstract
These data suggest that TLR4 plays a role in LIRI. Thus, TLR4 may be a potential therapeutic target to minimize ischemic-reperfusion-induced tissue damage and organ dysfunction.
Keywords
NF-κBHMGB1LPSJnkMIPTLRCPMc-Jun NH2-terminal kinaseAP-1ERKMCP-1BALBSAMPOMAPKLIRIbovine serum albuminischemia-reperfusioninterleukintumor necrosis factor-αToll-like receptorhigh-mobility group box 1counts per minutelung ischemia-reperfusion injuryTNF-αnuclear factor-κBbronchoalveolar lavagelipopolysaccharidemyeloperoxidasewild-typemacrophage inflammatory proteinmonocyte chemoattractant protein-1activator protein-1mitogen-activated protein kinaseKeratinocyte chemoattractant
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Authors
Akira MD, PhD, Timothy H. MD, Shin MD, Tomohito MD, Motoshi MD, PhD, Hideto MD, PhD,