The impact of dyslipidaemia on cardiovascular mortality in individuals without a prior history of diabetes in the DECODE Study

Article ID	Journal	Published Year	Pages	File Type
2893308	Atherosclerosis	2009	5 Pages	PDF

Abstract

Low HDL-C and high TC/HDL-C increase CVD mortality in either diabetic or non-diabetic individuals defined based on the fasting glucose criteria, but not the 2-h criteria. TG is a significant CVD risk predictor only in the presence of combined hyperglycaemia or diabetes. The difference between fasting and post-load hyperglycaemia with regard to the lipid-CVD relation may suggest a different pathophysiology underlying these two prediabetic states.

Keywords

FPG 2hPG NFG IPH NGT IFG HDL-C IGT impaired glucose tolerance Impaired fasting glucose cardiovascular disease normal glucose tolerance Triglycerides CVD Decode non-HDL-C confidence interval Fasting plasma glucose high-density lipoprotein cholesterol Lipid Mortality hazard ratio Hyperglycaemia total cholesterol Non-HDL cholesterol Normal fasting glucose

Related Topics

Health Sciences Medicine and Dentistry Cardiology and Cardiovascular Medicine

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The impact of dyslipidaemia on cardiovascular mortality in individuals without a prior history of diabetes in the DECODE Study

Authors

Lei Zhang, Qing Qiao, Jaakko Tuomilehto, Niklas Hammar, Giacomo Ruotolo, Coen D.A. Stehouwer, Robert J. Heine, Mats Eliasson, Björn Zethelius, for the DECODE Study Group for the DECODE Study Group,