| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2894444 | Atherosclerosis | 2007 | 6 Pages |
Abstract
In the present study, we show that X447 homozygotes exhibit enhanced apoB48 clearance. Previously, these homozygotes were shown to present with enhanced apoB100 TRL conversion. Combined, this LPLS447X gain of function variant affects apoB48 as well as apoB100 TRL metabolism.
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Authors
Melchior C. Nierman, Jaap Rip, Jan Albert Kuivenhoven, Naohiko Sakai, John J.P. Kastelein, Monique G.M. de Sain-van der Velden, Erik S.G. Stroes, Berthil H.C.M.T. Prinsen,