Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2894719 | Atherosclerosis | 2008 | 9 Pages |
Abstract
These results demonstrated that PEDF administration could inhibit occlusive thrombus formation by blocking the platelet activation and aggregation through its anti-oxidative properties. Our present study suggests that pharmacological up-regulation or substitution of PEDF may offer a promising strategy for the treatment of arterial thrombosis.
Keywords
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Authors
Katsuhiko Takenaka, Sho-ichi Yamagishi, Takanori Matsui, Kazuo Nakamura, Yuko Jinnouchi, Yumiko Yoshida, Shin-ichiro Ueda, Yoshio Katsuki, Yousuke Katsuda, Tsutomu Imaizumi,