Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2899207 | Cardiovascular Pathology | 2008 | 9 Pages |
Abstract
This transgenic model provides evidence that TAg-induced cell cycle reentry is associated with a complex modulation of the collageneous matrix. Factors identified in this in vitro study reveal a comprehensive expression pattern of candidates, which might allow the vessel to undergo adaptive arterial remodeling under in vivo conditions. Our results will give rise to further investigations to elaborate on this hypothesis and to improve understanding of the role of such factors in vascular diseases.
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Authors
Jürgen R. Sindermann, Christiane Köbbert, Reinhard Voss, Jan Ebbing, Keith L. March, Günter Breithardt, Gabriele Weissen-Plenz,