Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2899332 | Cardiovascular Pathology | 2011 | 5 Pages |
Abstract
Primary cardiac angiosarcoma is a rare neoplasm and the epithelioid variant is exceedingly rare. We report a case of an epithelioid angiosarcoma that involved the right atrium and aorta of a 47-year-old male. The patient presented with atrial fibrillation and presyncopal spells. Following clinical evaluation, including computed tomography scan and trans-esophageal echocardiography, the neoplasm was surgically removed. It was a poorly differentiated malignant neoplasm composed of medium-sized epithelioid cells with a moderate amount of amphophilic cytoplasm. Immunohistochemical staining, including positive staining for CK22, AE1/AE3, melan-A, vimentin, and CD31, indicated the neoplasm was best categorized as an epithelioid angiosarcoma.
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Authors
Lise Anne Marie Matzke, Margaret A. Knowling, Dennis Grant, James B. Cupples, Jonathon Leipsic, Andrew Ignaszewski, Michael F. Allard,