Normal Values and Thresholds for the Clinical Interpretation of Exhaled Nitric Oxide Levels in the US General Population

Assuming 95% of the healthy US general population had no clinically significant airway inflammation as assessed by FENO, values exceeding the 95th percentiles indicated abnormality and a high risk of airway inflammation. A large variation of normal FENO values existed in the general population, which was poorly predicted by multiple linear regression models.