Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2904811 | Chest | 2005 | 4 Pages |
Abstract
An abbreviated challenge using a single bolus dose of AMP grossly underestimates bronchial hyperresponsiveness. Although the pharmacologic half-life of AMP is short (90 s), the lesser response and shortened recovery with the abbreviated challenge suggest a more prolonged physiologic half-life, which in turn may have implications for abbreviated challenge protocols
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Authors
Fardon MA, MB Bchir, Hodge BMSc, Lipworth MD,