| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2905453 | Chest | 2006 | 12 Pages |
Abstract
No definitive clinical benefits related to the administration of retinoids were observed in this feasibility study. However, time- and dose-dependent changes in Dlco, CT density mask score, and health-related QOL were observed in subjects treated with ATRA, suggesting the possibility of exposure-related biological activity that warrants further investigation.
Keywords
TLCSGRQQOLDLCOQuality of life13-cis retinoic acidatRAall-trans retinoic acidEmphysemaPulmonary function testAlveolar volumeResidual volumeHigh doselow doseRadiographRetinoic aciddiffusing capacity of the lung for carbon monoxideTotal lung capacityCT scanhounsfield unitSt. George respiratory questionnaireClinical trialHealth-related quality of life
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Authors
Roth MD, FCCP, Connett PhD, D'Armiento MD, PhD, Foronjy MD, Friedman MD, Goldin MbChb, PhD, Louis PhD, Mao MD, FCCP, Muindi MD, PhD, O'Connor MD, FCCP, Ramsdell MD, FCCP, Ries MD, FCCP, Scharf MD, PhD, Schluger MD, Sciurba MD, FCCP, Skeans MS,