Microalbuminuria and Prediction of Cardiovascular Complications in Patients with Coronary Artery Disease and Type 2 Diabetes Mellitus after CABG Surgery

BackgroundThis investigation was aimed at assessing the clinical significance of microalbuminuria (MA) in predicting in-hospital adverse outcomes amongst the patients with coronary artery disease (CAD) and type 2 diabetes mellitus (DM) who have undergone coronary artery bypass graft (CABG) surgery.MethodsWe recruited 720 consecutive Caucasian (Russian) patients who underwent CABG surgery during 2011-2012.ResultsPatients with renal dysfunction (RD) and without type 2 DM had significantly higher median serum creatinine seven days after CABG surgery compared to patients without RD and type 2 DM. There were no statistically significant intergroup differences regarding glomerular filtration rate. However, the highest median of urine albumin excretion 24 hours before and seven days after CABG surgery was detected in patients with RD and type 2 DM whilst the lowest median was noted in patients without RD and type 2 DM. Median of urine albumin excretion 24 hours before and seven days after CABG surgery in patients with adverse outcome was significantly higher compared to patients with a favourable outcome.ConclusionsWe suggest that the determination of MA before and after CABG surgery may assist in predicting adverse outcomes after CABG surgery.