Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2917826 | Heart, Lung and Circulation | 2015 | 7 Pages |
Abstract
The dose response of epinephrine is distinct for vascular tone, HR and contractility. The need for higher doses to see cardiac effects is likely due to the threshold for drug accumulation in tissue. Successful inotropic support with epinephrine cannot be achieved unless the infusion is sufficient to raise the heart rate.
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Authors
Mikhail Y. MD, PhD, Abraham E. BA, Matthew J. BA, Elazer R. MD, PhD, Mark A. MD, PhD,