Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2920587 | Heart, Lung and Circulation | 2006 | 6 Pages |
Abstract
The oxidative stress imposed on lung tissue, as seen by high levels of lipid peroxidation, after brain injury was significantly attenuated by MPSS treatment. MPSS treatment following brain injury also augmented putative anti-apoptotic Bcl-2 gene expression in lung tissue. Further studies are required to determine the full range and lower limits of effective MPSS dose. More importantly the optimal efficacy according to the timing of MPSS treatment after brain injury needs to be determined for impact on more diverse markers of cell inflammation, apoptosis and injury.
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Authors
Erkan MD, FETCS, Kanat MD, Pinar MD, Mustafa MD, Engin MD, Müge PhD, Serdar MD, Kamer MD,