Article ID Journal Published Year Pages File Type
2927190 IJC Metabolic & Endocrine 2015 4 Pages PDF
Abstract

The presence of impaired kidney function during heart failure and vice versa is a frequent occurrence. This situation is defined “Cardio-renal Syndrome”.In the Cardio-renal Syndrome (CRS) are included 5 different sub-syndromes defined on the basis of the organ primitively responsible: Acute Cardio-renal Syndrome (Type 1), Chronic Cardio-renal Syndrome (Type 2), Acute Reno-cardiac Syndrome (Type 3), Chronic Renal-cardiac Syndrome (Type 4) and Secondary Cardio-renal Syndrome (Type 5).The physiopathologic mechanisms underlying CRS are still partially obscure, but, a key role seems to be played by the renin-angiotensin-aldosterone axis.Therapeutic strategies involved in CRS treatment include the use of diuretics, ACE inhibitors, Angiotensin Receptor Blockers and β-Blockers, emphasizing the role of a proper use of medication indicated for the treatment of cardiac decompensation.

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