Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2931777 | International Journal of Cardiology | 2010 | 5 Pages |
Abstract
Coronary artery disease (CAD), chronic heart failure (CHF) or chronic obstructive pulmonary disease (COPD) occur commonly in the presence of each other and are associated with similar systemic inflammatory reactions. Inflammation plays a central role in the pathogenesis of these diseases. C-reactive protein (CRP) could represent the sentinel biomarker to all chronic diseases. Also, interleukin (IL)-6 may play a causal role in systemic inflammatory diseases. These complex interactions between heart and lung can be denoted as ‘cardiopulmonary continuum’. Common risk factors induce systemic inflammatory processes which lead to progression of atherosclerotic diseases as well as COPD.
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Authors
Christian Ukena, Felix Mahfoud, Michael Kindermann, Ingrid Kindermann, Robert Bals, Adriaan A. Voors, Dirk J. van Veldhuisen, Michael Böhm,