Article ID Journal Published Year Pages File Type
2931777 International Journal of Cardiology 2010 5 Pages PDF
Abstract

Coronary artery disease (CAD), chronic heart failure (CHF) or chronic obstructive pulmonary disease (COPD) occur commonly in the presence of each other and are associated with similar systemic inflammatory reactions. Inflammation plays a central role in the pathogenesis of these diseases. C-reactive protein (CRP) could represent the sentinel biomarker to all chronic diseases. Also, interleukin (IL)-6 may play a causal role in systemic inflammatory diseases. These complex interactions between heart and lung can be denoted as ‘cardiopulmonary continuum’. Common risk factors induce systemic inflammatory processes which lead to progression of atherosclerotic diseases as well as COPD.

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